Me You Madness tells the deliciously wicked tale about a beautiful, ruthlessly ambitious, and successful businesswoman, Catherine Black. She lives a life of luxury living in her architectural dream house in Malibu, collecting designer fashion, fast cars, and exquisite jewellery. She has no need for a man, except to satisfy her natural serial killer instinct, literally. When a petty thief responds to her online roommate ad, he thinks he's struck gold...but he has no idea that after a night of partying and passion, he is really just on her menu to be her next victim.