What do a wacky nightclub mermaid, a failed ex-golfer, a wise-cracking kid and a killer have in common?? They're all "Off and Running"in this wacked out comedy of life, death, success, failure? and horse-racing.

Cyndi Lauper stars as Cyd, a performing mermaid in a Miami Hotel who has just fallen in love with a horse trainer called Woody. But their love is barely out of the gate when Woody's champion horse Molnir - and then Woody himself - are murdered. The trainer's dying act is to slip a locket into Cyd's outstretched hand and before she has time to think, she's out of her mermaid flippers and on the road, being hotly pursued by Woody's killer.

Why has a champion race-horse and its trainer been murdered? And what is the secret of the mysterious locket? With the help of Jack, a failed golf-pro, and Pompey, a precocious ten year old kid, Cyd is going to have to risk her life to find out - whether she wants to or not!